Low osmolality contrast & premedication helps. The higher the iodine concentration, the greater the risk of an adverse reaction. A non-iodinated contrast media is one that does not contain iodine and may instead contain barium or other non-iodinated media as the radio opaque substance. Alternative to iodine contrast for CT colonograghy ? Iodinated contrast media are toxic to the kidneys and kidney functions. Hi all, I urgently need to have a scan of abdomen and pelvic area, but I’m allergic to the iodine contrast dye that they inject. This causes the same reaction as the histamine release due to allergy. Shellfish allergy has nothing to do with iodine or contrast. ... is there another alternative to this dye. The body part with the contrast inside will appear lighter on the radiographic image than the surrounding tissue. Back to top Preventing an Allergic Reaction to Contrast with Medication About Contrast Dye. Obviously speak with your physician about what to do. Computed tomography (CT) scans and magnetic resonance imaging (MRI) use different kinds of contrast. Some of it depends on how bad the kidney disease IS and what type. Foss • • 16 Replies. locations for imaging of patients with prior history of allergy to iodine. The iodine concentration has an effect on the severity of an adverse reaction. Has anyone had a similar problem and if so how did you overcome it. Rather, contrast media act to directly release histamine and other chemicals from mast cells. Contrast media is used in radiography to increase the clarity of the image. Patients are frequently asked about iodine or seafood allergy before IV contrast material is administered because of a commonly held belief among radiologists and others in the medical community of a specific cross-reactivity between iodinated radiographic contrast material and other iodine-rich substances. Strictly speaking, a reaction to an iodine-based dye is not the same thing as an allergy to iodine because it generally doesn’t stem from the same type of immune-system response as a true allergy. I believe there are some options out there. Having a reaction to an iodine-based contrast dye is also not the same as an allergy to seafood, which may be rich in iodine. Sometimes, contrast dye (or contrast) is used in imaging scans to help your doctors see your organs better. Author: Prof Stacy Goergen* What is contrast medium? Requesting / Referring Physician to prescribe Premedication, to be initiated prior to the CT exam. The high concentration of the contrast can shock cells called basophils into releasing their granules filled with histamine. 4. "Iodine allergy" is often used as a collective term for adverse reactions to these agents. 3. Not a doctor; responding to A2A. 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